This research validates the model of cultural security in sustainable knowledge-based development. The research method is applied in terms of purpose and descriptive-survey in terms of data collection method and mixed (quantitative-qualitative) in terms of the type of data. The statistical population in the qualitative section (interview section) comprised 15 experts and specialists familiar with cultural and scientific issues in the Ministry of Science, Research and Technology, who were selected by purposive sampling. The statistical population in the quantitative part included 551 experts and managers of the Ministry of Science, Research and Technology in 2019-20, from among whom, some 226 persons were selected by stratified random sampling. Both library research and field observation methods were employed for data collection. In the field observation method, in order to collect the qualitative part, interviews were conducted with a number of mangers enaged in cultural affairs, and in the quantitative part, the data was collected through a researcher-made questionnaire. The reliability of this questionnaire was estimated based on 0.86 Cronbach's alpha coefficient. Confirmatory factor analysis was used in relation to the validity of the obtained indices and also a questionnaire was designed to assess the validity of the model, which measured the dimensions of the final model using a single sample t-test. The results showed that the model was valid and the model of cultural security in the knowledge-based sustainable development gained the required validity with cultural, economic, social, environmental, political as well as national and religious factors.
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